Prof. CHEN, Hongying

　　Contact Information:

　　Mailing Address:

　　College of Life Sciences

　　Northwest A&F University

　　Yangling, Shaanxi 712100

　　P. R. China

　　Phone: (86) 29 87092853

　　Fax: (86) 29

　　E-mail: chenhy@nwsuaf.edu.cn

　　Office: North Campus, Science Building, College of Life Sciences, D212

　　

　　Research Interests:

　　1. virus-host interactions

　　2. Structure and function of viral proteins

　　3. Optimization of baculovirus expression system

　　

　　Education Experiences:

　　China Agricultural University, Animal Physiology and Biochemistry, Ph.D. 1998

　　China Agricultural University, Animal Physiology and Biochemistry, B.Sc. 1992

　　

　　Professional Experiences:

　　Professor in College of Life Science, Norwest A&F University (2009-present)

　　Research fellow in The University of Reading (2000-2009)

　　Postdoc in the Institute of Developmental Biology, Chinese Academy of Sciences (1998-2000)

　　

　　Recent Publications:

　　Chen J, Xu X, Tao H, Li Y, Nan H, Wang Y, Tian M, Chen H*. (2017) Structural Analysis of Porcine Reproductive and Respiratory Syndrome Virus Nonstructural Protein 7α (NSP7α) and Identification of its Interaction with NSP9. Front. Microbiol. , 8:853.

　　Chen J, Xu X, Tao H, Wang Y, Chen H*. (2016) Chemical shift assignments of nsp7α from porcine reproductive and respiratory syndrome virus. Biomol NMR Assign. , 10(2):391-394.

　　Dong S, Liu L, Wu W, Armstrong SD, Xia D, Nan H, Hiscox JA, Chen H*. (2016) Determination of the interactome of non-structural protein12 from highly pathogenic porcine reproductive and respiratory syndrome virus with host cellular proteins using high throughput proteomics and identification of HSP70 as a cellular factor for virus replication. Journal of Proteomics, 146: 58–69.

　　Liu L, Tian J, Nan H, Tian M, Li Y, Xu X, Huang B, Zhou E, Hiscox JA, Chen H*. (2016) Porcine Reproductive and Respiratory Syndrome Virus Nucleocapsid Protein Interacts with Nsp9 and Cellular DHX9 to Regulate Viral RNA Synthesis. J Virol., 90:5384–5398.

　　Xu X*, Zhou X, Nan H, Zhao Y, Bai Y, Ou Y, H Chen*. (2016) Aggregation of AcMNPV LEF-10 and Its Impact on Viral Late Gene Expression. PLoS ONE, 11(5): e0154835.

　　Y Wang, Y Mao, X Xu, S Tao*, H Chen*. (2015) Codon Usage in Signal Sequences Affects Protein Expression and Secretion Using Baculovirus/Insect Cell Expression System. PLoS ONE 10(12): e0145887.

　　Liu L, Lear Z, Hughes DJ, Wu W, Zhou E, Whitehouse A, Chen H *, Hiscox JA *. (2015) Resolution of the cellular proteome of the nucleocapsid protein from a highly pathogenic isolate of porcine reproductive and respiratory syndrome virus identifies PARP-1 as a cellular target whose interaction is critical for virus biology. Veterinary Microbiology, 176(1-2): 109-119.

　　Wu F, Peng K, Tian J, Xu X, Zhou E, Chen H*. (2014) Immune response to Fc tagged GP5 glycoproteins of porcine reproductive and respiratory syndrome virus. Viral Immunology , 27 (7): 343–349.

　　Liu B, Wang R, Wu F, Xu X, Chen H*. (2014) Rapid production of HIV-1 neutralizing antibodies in baculovirus infected insect cells. Protein Expression and Purification, 99(-): 87-93.

　　Xu X, Chen Y, Zhao Y, Liu X, Dong B, Jones IM, Chen H*. (2013) Baculovirus superinfection: A probable restriction factor on the surface display of proteins for library screening. PLoS ONE, 8(1): e54631.